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WebDec 29, 2014 · EZH2 is the catalytic subunit of this complex and is overexpressed or mutated, and associated with H3K27me3, in several cancer types, including breast, … Cancer is characterized by uncontrolled cell growth that arises from the progressive acquisition of a small number of point mutations or aneuploidy related to cell proliferation, differentiation, apoptosis and cell-to-cell communication (1,2). Tumor suppressor genes (TSGs) generally refer to a class of cancer … See more We set up a MySQL relational database to store all the data. A user-friendly web interface for browsing and searching was implemented by Perl CGI and JavaScript. See more Funding for open access charge: National Institutes of Health [R01LM011177 and P30CA68485]. Conflict of interest statement. None declared. See more TSGene is the first attempt to establish a literature-based resource of tumor suppressor by integrating genomic data of mutations, gene expressions, regulations, methylations and interactions. It is a valuable resource for … See more WebJun 1, 2011 · Gastric cancer (GC) has continued to be a threat to human life. Diagnosis of GC at advanced stage is considered as a major reason for lower overall five-year survival rate in developing countries. easy heavy hors d\u0027oeuvres recipes