WebDec 22, 2024 · Below is a text only representation of the Patient Information Leaflet (ePIL). The text only version may be available in large print, Braille or audio CD . For further information call emc accessibility on 0800 198 5000 . The product code (s) for this leaflet is: PL 12762/0596. Print patient leaflet as text only. WebSummary. This Scientific Impact Paper reviews existing evidence-based guidance from the Medicines and Healthcare products Regulatory Agency (MHRA) and European Medicines …
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WebPethidine is a narcotic analgesic with similar actions to morphine. Pharmacokinetics: Pethidine is extensively distributed throughout the body with a distribution volume of 200-300L. It is 40 - 65% plasma bound and can cross the placenta. 70% of a dose is excreted in the urine in 24 hours. 5 – 30% is unchanged depending on the pH of the urine. WebThe side effects of pethidine increase with repeated dosing and so the medicine is not often used to treat pain. Repeated dosing, especially in people with poor kidney function, can also lead to neural (nerve) conditions such as tremors, twitches and seizures. Other side effects include: lightheadedness. sedation. literacy definition pdf
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WebJan 19, 2024 · Pethidine for pain relief. Pethidine is used to treat pain, particularly during childbirth. It is usually given by injection and provides pain relief for up to four hours. The … WebJan 19, 2024 · Pethidine for pain relief. Pethidine is used to treat pain, particularly during childbirth. It is usually given by injection and provides pain relief for up to four hours. The most common side-effects are feeling dizzy or sleepy, sweating and feeling sick (nausea). WebDec 12, 2016 · Background The commonest opioid used for pain relief in labour is pethidine (meperidine); however, its effectiveness has long been challenged and the drug has known side effects including maternal sedation, nausea and potential transfer across the placenta to the foetus. Over a third of women receiving pethidine require an epidural due to … literacy delaware