Phospho stat3

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August undefined, 2024

WebUse Anti-phospho-STAT3 (Tyr705) Antibody, clone 9E12 (Mouse Monoclonal Antibody) validated in ELISA, IP, WB to detect phospho-STAT3 (Tyr705) also known as Acute-phase response factor or DNA-binding protein APRF. This Stat3 Antibody has been validated in Human, Mouse and Canine samples. Quality WebBrilliant Violet 421™ anti-STAT3 Phospho (Tyr705) Antibody. Human whole blood was stimulated with (top) or without (bottom) IL-6 for 15 minutes, then treated with RBC …

Brilliant Violet 421™ anti-STAT3 Phospho (Tyr705) Antibody

WebNov 15, 2002 · As shown in Fig. 3,A, phospho-Stat3 is detected in the nucleus with different intensities in all three of the human prostate cancer cell lines examined. The intensity of red stain (Nova-Red) corresponds to the level of active phospho-Stat3, whereas the blue stain (hematoxylin) is the counterstain. WebSignal transducer and activator of transcription 3 (STAT3) is a latent cytoplasmic transcription factor. It is activated by cytokines, including interleukin-6 (IL-6) through … grand majestic theater branson

pSTAT3: a target biomarker to study the pharmacology of the anti …

WebSTAT3: Products The STAT family of transcription factors, first described as key mediators of interferon signal transduction, are now recognized as signaling factors downstream of many cytokines, growth factors, and hormones. At … WebPhospho-Stat3 (Tyr705) Antibody detects endogenous levels of Stat3 only when phosphorylated at Tyr705. The antibody does not cross-react with other Stat proteins … WebNitro-oleic acid (NO2-OA), pluripotent cell-signaling mediator, was recently described as a modulator of the signal transducer and activator of transcription 3 (STAT3) activity. In our … grand majestic theatre

PE anti-EGFR Phospho (Tyr845) Recombinant Antibody

Purified anti-STAT3 Phospho (Tyr705) Antibody - BioLegend

WebJul 8, 2024 · Here, we report that phospho-Tyr705 of STAT3 (pY-STAT3), not total STAT3, contributes to systemic inflammation and coagulopathy in sepsis. Methods: Cecal ligation … WebApr 12, 2024 · This was evidenced by the fact that the reduced phosphorylation of STAT3 at the Y705 position by stattic has unleashed these pro-metastatic functions of the cancer cells, leading to the increased presence of CSCs and to an EMT-like phenotype in the cells. The negative regulatory roles of Y705-STAT3 on CSC generation was also evidenced by … grandma josephine willy wonkaWebPhospho-STAT3 (Ser727) Polyclonal Antibody Advanced Verification This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. 2 Published Figures 15 References View all (92) STAT3 antibodies Catalog # 44-384G 100 µL USD 453.00 Check your price & availability Join Aspire™ for free antibodies Quantity chinese food near me 30342

"STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT3 is phosphorylated by receptor-associated Janus kinases (JAK), forms homo- or heterodimers, and translocates to the cell nucleus where it acts as a transcription activator. Specifically, STAT3 becomes activated … See more Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene. It is a member of the STAT protein family. See more Loss-of-function mutations in the STAT3 gene result in Hyperimmunoglobulin E syndrome, associated with recurrent infections as well as disordered bone and tooth development. See more • Hoey T, Grusby MJ (1999). STATs as mediators of cytokine-induced responses. Advances in Immunology. Vol. 71. pp. 145–62. See more STAT3 has been shown to interact with: • AR, • ELP2, • EP300, • EGFR, • HIF1A, • JAK1, See more • FactorBook STAT3 See more " - Phospho stat3

Phospho stat3

STAT3-Mediated Signaling Dysregulates Lung Fibroblast …

WebThe STAT3 Phospho (Tyr705) antibody recognizes the regulatory tyrosine phosphorylation of human STAT3 protein and has been shown to be useful for Western blotting. During PD … WebApr 11, 2024 · STAT3 is widely expressed in organs and tissues, and the phosphorylation of STAT3 motivates downstream genes related to proliferation and apoptosis, thus performing proliferation effects. A previous study has revealed that the motivation of STAT3 signaling promotes colonic mucus secretion in DSS-induced colitis in mice ( 28 ).

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WebApr 10, 2024 · The fluorescence of phosphorylation-STAT3 was significantly upregulated in the induction group, while decreased in addition of Stattic (Fig. 6A, F). The expression profile of osteogenic genes including ALPL, RUNX2 and BMP2 (Fig. 6B–D) and proteins including BGLAP (Fig. 6E) and ALP (Fig. 6G) was in consistent with phosphorylation-STAT3. WebSTAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the …

WebThe BD CBA Phospho Stat3 (Y705) Flex Set must be used in conjunction with a BD CBA Cell Signaling Master Buffer Kit (Cat. No. 560005, 100 tests, or 560006, 500 tests) and a flow … Web4% PFA plus methanol. Methanol only. This clone failed to immunoprecipitate EGFR Phospho (Tyr845) from whole cell extracts prepared from EGF-stimulated A-431 cells. This recombinant antibody clone is derived from clone A18028A. This clone is predicted to recognize the region corresponding to EGFR Phospho (Tyr845) in both rat (Tyr846) and …

WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-STAT3 (phospho S727) antibody [E121-31] (ab32143) Research with … WebPhospho-Stat3 (Tyr705) (3E2) Mouse mAb detects endogenous levels of Stat3 only when phosphorylated at tyrosine 705. The antibody does not significantly cross-react with other members of the Stat family. Species Reactivity: Human, Mouse, Rat, Monkey Species predicted to react based on 100% sequence homology:

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WebMar 21, 2024 · STAT3 (Signal Transducer And Activator Of Transcription 3) is a Protein Coding gene. Diseases associated with STAT3 include Autoimmune Disease, Multisystem, Infantile-Onset, 1 and Hyper-Ige Recurrent Infection Syndrome 1, Autosomal Dominant . Among its related pathways are IL-9 Signaling Pathways and Prolactin Signaling . grand makadi hotel red sea holidaysWebBrilliant Violet 421™ anti-STAT3 Phospho (Tyr705) Antibody. Human whole blood was stimulated with (top) or without (bottom) IL-6 for 15 minutes, then treated with RBC Lysis/Fixation Solution, and permeabilized with True-Phos™ Perm Buffer, then stained with CD3 APC and STAT3 pY705 (clone 13A3-1) Brilliant Violet 421™. chinese food near me 32809WebPhospho-Stat3 (Tyr705) (D3A7) XP ® Rabbit mAb (Alexa Fluor ® 750 Conjugate) detects endogenous levels of Stat3 only when phosphorylated at Tyr705. This antibody does not cross-react with phospho-EGFR or the corresponding phospho-tyrosines of other Stat proteins. Species Reactivity: Human, Mouse, Rat, Monkey grandmake technologyWebDec 1, 2024 · STAT3 phosphorylation at Ser727 and Tyr705 differentially regulates the EMT–MET switch and cancer metastasis Wei-Hsin Lin, Yi-Wen Chang, Min-Xiang Hong, Te … grandma kay\u0027s chicken enchiladasWebWestern blot - Phospho-STAT3-Y705 Rabbit pAb (AP0070) Western blot analysis of extracts of HeLa cells, using Phospho-STAT3-Y705 antibody (AP0070) at 1:500 dilution.HeLa cells were treated by IFN-α (100 ng/ml) at 37℃ for 30 minutes after serum-starvation overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. grandma josie\u0027s amish white tomatoWebMay 7, 2015 · STAT3 (signal transducer and activator of transcription 3 [acute-phase response factor]) is a latent transcription factor that mediates extracellular signals such as cytokines and growth factors through interaction with polypeptide receptors at the cell surface.6STAT3 protein becomes transcriptionally activated primarily by tyrosine … grandma jo\u0027s clifford ontarioWebMay 7, 2015 · The literature suggests a modulatory role for Ser727 phosphorylation in STAT3 transcriptional activation, presumably through the enhanced recruitment of … grandma josephine\u0027s christmas cookies recipe