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Phospho eif4b

WebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and … WebPhospho-eIF4B (Ser406) Antibody detects endogenous levels of eIF4B protein only when phosphorylated at Ser406. Species Reactivity: Human, Mouse. Species predicted to react …

Loss of SLC25A11 causes suppression of NSCLC and melanoma …

WebSep 5, 2024 · eIF4B phosphorylation patterns in hippocampal neurons and cortical astrocytes. ( A) Western blot analysis of total cell extracts from neurons or astrocytes … WebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. greek yogurt with least amount of sugar https://cyborgenisys.com

Abrogating phosphorylation of eIF4B is required for EGFR and

WebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins are EIF4A, EIF4F. eIF4B is involved in translation of numerous proliferative or anti-apoptotic mRNAs with highly structured 5'UTR and subsequently affect cell growth … WebJan 25, 2024 · We hypothesised that the effect of SLC25A11 knockdown on inhibiting protein translation was mediated by the inactivation of translational elongation factors … WebAug 17, 2014 · Phospho-proteomics identified the mTOR pathway to be of interest in EGFR inhibitor resistance. In our studies, combining gefitinib and temsirolimus decreased cell growth and survival in a synergistic manner. Our data identified eIF4B, as a potentially key fragile point in EGFR and mTOR inhibitor synergy. greek yogurt with granola and berries

Human Phospho-eIF4B (S422) Antibody MAB3800: R&D Systems

Category:Phospho-EIF4B-S422 Rabbit pAb-Phospho-specific Antibodies

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Phospho eif4b

The mTOR/PI3K and MAPK pathways converge on eIF4B to …

WebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins … WebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP.

Phospho eif4b

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WebPhospho-EIF4B (Ser406) EIF4B (Eukaryotic Translation Initiation Factor 4B) is a Protein Coding gene. Among its related pathways are Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include nucleic acid binding ... WebAll lanes : Anti-eIF4B (phospho S504) antibody [EP2261Y] (ab75823) at 1/50000 dilution Lane 1 : 293T cell lysate, untreated Lane 2 : 293T cell lysate, treated with AP Lysates/proteins at 10 µg per lane. Secondary All lanes : goat anti-rabbit HRP at 1/2000 dilution Predicted band size: 69 kDa Observed band size: 69 kDa

WebOct 6, 2008 · Insulin stimulation resulted in phosphorylation of eIF4B as detected by both the phospho-eIF4B Ser422 antibody as well as the phospho-PKB substrate antibody (Figure 5a, lanes 1 and 2). WebProduct Details Target Information The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP.

Web人载脂蛋白A4(Apo-A4)ELISA试剂盒 ;英文名称: Human Apo-A4 ELISA Kit ;实验名称: 人载脂蛋白A4(Apo-A4)ELISA试剂盒 ;实验别名: 人载脂蛋白A4(Apo-A4)ELISA试剂盒 48T/96T ;规格: 48T/96T 报价 人载脂蛋白A4(Apo-A4)ELISA试剂盒实验目的:本试剂盒仅供研究使用 ,用于 用于测定血清、血浆及相关液体样本中待测物质 ... WebeIF4B (eukaryotic translation initiation factor 4B), an RNA binding protein, is essential for the binding of mRNA to the 43S pre-initiation complex, which consists of the 40S ribosomal …

WebHuman Phospho-eIF4B (S422) Antibody Summary Species Reactivity Human Specificity Detects human eIF4B when phosphorylated at S422 Source Monoclonal Rat IgG 2A Clone # 866049 Purification Protein A or G purified from hybridoma culture supernatant Immunogen Phosphopeptide containing the human eIF4B S422 site Formulation

WebPhospho-EIF4B-S422 Rabbit pAb (AP0278) Datasheet SDS Tested applications: WB IHC Reactivity: Human, Mouse Western blot analysis of extracts from HeLa cells using phospho-EIF4B-S422 antibody (AP0278). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. greek yogurt with less sugarWebJun 8, 2006 · eIF4B Ser422 phosphorylation persists in cells lacking S6K1 and S6K2 To further corroborate the existence of an eIF4B kinase that is distinct from S6K in cells … flower first vermontWebWestern blot analysis of extracts from HeLa cells, untransfected or transfected with SignalSilence ® eIF4B siRNA #6416, using Phospho-eIF4B (Ser422) Antibody (upper) or eIF4B Antibody #3592 (lower). 48 hours following transfection, cells were treated with Rapamycin (50 nM) and U0126 (10 uM) as indicated. flower firm chicago ilWebProduct Details Target Information The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. flower first birthdayWebApr 6, 2024 · The protein expression of mTOR, phospho-mTOR, p70 S6 kinase (p70 S6K), phospho-p70 S6K, eIF4B, phospho-eIF4B, eIF4G, 4E-BP1, phospho-4E-BP1, eIF4E, phospho-eIF4E, and Rpb1 in the liver was assessed using western blotting. Actin was used as the loading control. (Specific antibody information is provided in the Supplementary Materials.) flowerfirstvt gmail.comWebAll lanes : Anti-eIF4B (phospho S504) antibody [EP2261Y] (ab75823) at 1/50000 dilution Lane 1 : 293T cell lysate, untreated Lane 2 : 293T cell lysate, treated with AP … flower first namesWebInvitrogen Anti-Phospho-EIF4B (Ser504) Polyclonal, Catalog # PA5-114571. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Immunohistochemistry (PFA fixed) … greek yogurt with oats