Dynein intermediate chain 2 ciliary
WebDec 8, 2024 · The human dynein intermediate chain 2 gene (DNAI2): cloning, mapping, expression pattern, and evaluation as a candidate for primary ciliary dyskinesia. … Web1 day ago · First, deployment of the ODA intermediate chain Dnai2 lagged well behind Enkur and overall axoneme growth as reported by memRFP (Fig. 4 C), and when co-expressed, ... The ciliary inner dynein arm, I1 dynein, is assembled in the cytoplasm and transported by IFT before axonemal docking. Cytoskeleton (Hoboken) ...
Dynein intermediate chain 2 ciliary
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WebHarper's Ferry / Washington County. Bollman Truss Bridge (abutments) [1] CSX. Harper's Ferry / Washington County. Virginia / Maryland. Sandy Hook Bridge. US 340. Loudoun … WebThe \{IFT\} dynein-2 motor complex that regulates ciliary retrograde protein transport contains a heavy chain dynein ATPase/motor subunit, DYNC2H1, along with other less well functionally defined subunits. ... thoracic dystrophy). \{WDR34\} encodes a \{WD40\} repeat-containing protein orthologous to Chlamydomonas FAP133, a dynein intermediate ...
WebJul 8, 2009 · The human dynein intermediate chain 2 gene (DNAI2): cloning, mapping, expression pattern, and evaluation as a candidate for primary ciliary dyskinesia. Source: Springer Science and Business Media LLC To beat or not to beat: roles of cilia in development and disease WebSep 26, 2024 · Dynein-associated light and intermediate chains regulate the biophysical mechanisms of axonemal dynein. Tctex-type outer arm dynein light chain 2 ... In summary, we identified TbLC2 as a ciliary …
WebFeb 5, 2013 · - Caused by mutation in the dynein, axonemal, intermediate chain 2 gene (DNAI2, 605483.0001) Close. Primary ciliary dyskinesia - PS244400 - 48 Entries ... Loges et al. (2008) reported a consanguineous Iranian Jewish kindred in which 2 individuals had primary ciliary dyskinesia characterized by neonatal pneumonia, recurrent rhinitis and ... WebMar 1, 2024 · The dynein-2 complex drives retrograde ciliary protein trafficking by associating with the intraflagellar transport (IFT) machinery, containing IFT-A and IFT-B …
WebDec 28, 2010 · Many individuals with PCD have a mutation in a gene encoding a component of the outer dynein arms (molecular motors that power the 9+2 ciliary cytoskeleton or axoneme), particularly in one of the ...
WebDec 16, 2013 · Dynein intermediate chain 2 (DNAI2) may be a candidate gene for PCD/KS according to a report by Pennarun et al.50 It comprises 14 exons, ... Liu Y, et al. CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nat Genet. 2012; 44:714–9. [PMC free article] [Google Scholar] the peter rabbit libraryWebNov 17, 2008 · Specific Antibodies Localize the Human Axonemal Outer Dynein Arm Intermediate Chain 2 (DNAI2) to the Respiratory Ciliary Axoneme and Sperm Tail (A) Western blot analysis of protein extracts from human nasal cell culture (M, protein standard; lane 1, silver staining). DNAI2 antibodies specifically detect a single band with the … sicilian levenfishWebTo ensure continuity of service, the facility maintains N+2 generator redundancy. 4Q22 Northern Virginia Data Center Market Report. GET ACCESS. About IAD02 Data Center. … sicilian living roomWebPrimary ciliary dyskinesia. At least 21 mutations in the DNAI1 gene have been found to cause primary ciliary dyskinesia, which is a condition characterized by respiratory tract … the peters brandWebNM_023036.6(DNAI2):c.124G>A (p.Val42Met) AND Primary ciliary dyskinesia 9 Clinical significance: Likely benign (Last evaluated: Jan 13, 2024) Review status: 1 star out of maximum of 4 stars sicilian lawyer hunts downWebFeb 5, 2013 · 605483 - DYNEIN, AXONEMAL, INTERMEDIATE CHAIN 2; DNAI2 - DNAI2 In 3 patients with primary ciliary dyskinesia-9 (CILD9; 612444), Loges et al. (2008) … sicilian lemon swiss rollEach molecule of the dynein motor is a complex protein assembly composed of many smaller polypeptide subunits. Cytoplasmic and axonemal dynein contain some of the same components, but they also contain some unique subunits. Cytoplasmic dynein, which has a molecular mass of about 1.5 megadaltons (MDa), is a dimer of dimers, containing approximately twelve polypeptide sub… sicilian lawyer